bioRxiv
Most Recent
Disease markers
Development and Validation of a Liquid-Liquid Phase Separation-Related Gene Signature as Prognostic Biomarker for Low-Grade Gliomas
Frontiers in oncology
Single cell sequencing analysis and transcriptome analysis constructed the liquid-liquid phase separation(LLPS)-related prognostic model for endometrial cancer
The FEBS Journal
Potential roles of super enhancers in inflammatory gene transcription
Experimental & molecular medicine
Phase separation of low-complexity domains in cellular function and disease
Nature communications
Exploration of nuclear body-enhanced sumoylation reveals that PML represses 2-cell features of embryonic stem cells
Experimental hematology & oncology
p53 amyloid aggregation in cancer: function, mechanism, and therapy
Cancers
The Long and the Short of It: NEAT1 and Cancer Cell Metabolism
bioRxiv
SLX4 assembles nuclear condensates that compartmentalize the SUMO-RNF4 pathway and drive DNA repair
Sep
20
Cold Spring Harbor Laboratory meeting on Epigenetics & Chromatin (2022)
Tuesday, September 20, 2022 | Cold Spring Harbor, NY, United States
Angewandte Chemie (International ed in English)
Mechanistic Insights into the Phase Separation Behavior and Pathway-Directed Information Exchange in all-DNA Droplets
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Emerging Implications of Phase Separation in Cancer
Oncogene
A novel lncRNA MTAR1 promotes cancer development through IGF2BPs mediated post-transcriptional regulation of c-MYC
International journal of biological macromolecules
Phase separation of p53 induced by its unstructured basic region and prevented by oncogenic mutations in tetramerization domain
Haematologica
Activation of lncRNA NEAT1 leads to survival advantage of multiple myeloma cells by supporting a positive regulatory loop with DNA repair proteins
Jill Bouchard
Editor in Chief, Condensates.com
The authors speculate that their results suggest paraspeckles may be a good therapeutic target for Multiple Myeloma.
bioRxiv
Phase separation of Myc differentially regulates gene transcription
Oncogene
CPEB3 suppresses gastric cancer progression by inhibiting ADAR1-mediated RNA editing via localizing ADAR1 mRNA to P bodies
Frontiers in oncology
Phase separation in epigenetics and cancer stem cells
Nature communications
Cytoplasmic forces functionally reorganize nuclear condensates in oocytes
Journal of hematology & oncology