Most Recent
Cellular and molecular life sciences : CMLS
Contributing editor, Condensates.com
Here's paper 2/2 this week about the complicated relationship between lncRNA NEAT1 transcripts, paraspeckles, and cancer.
iScience
Science advances
Contributing editor, Condensates.com
Here's paper 1/2 this week about the complicated relationship between lncRNA NEAT1 transcripts, paraspeckles, and cancer.
Thursday, September 24, 2020
American journal of cancer research
Contributing editor, Condensates.com
This review delves into what one needs to know in order to target stress granules to treat cancer.
Journal of cell science
Contributing editor, Condensates.com
This review does a nice job of describing the similarities and differences between stress granules and P bodies... obviously one of their commonalities is LLPS ;)
Nature reviews Molecular cell biology
Cancers
Contributing editor, Condensates.com
With so many of these proteins being involved in condensate formation, I'm sure one strategy for therapeutic intervention will to affect phase separation.
bioRxiv
Dartmouth College | Hanover, NH
ApplyBiochimica et biophysica acta Proteins and proteomics
Contributing editor, Condensates.com
Have you heard of NPM1's role in the phase separation that happens within the nucleolus? If not, this review should get you up to speed.
University of Texas at Austin | Austin, TX
ApplyCell
BioRxiv
Essays in biochemistry
Contributing editor, Condensates.com
Here's a nice review breaking down how several proteins make up the core-shell architecture of paraspeckles.
Aging cell
Contributing editor, Condensates.com
Here's an article about an interaction inside nuclear speckles that has interesting implications for the aging process.
Molecular Cell
Contributing editor, Condensates.com
Here's a commentary on the big Science paper about cancer drugs going to nuclear condensates.
Pharmacological research
Contributing editor, Condensates.com
Here's a nice review discussing how stress granules are involved in various diseases and may be targeted therapeutically.
Scientific Reports
Contributing editor, Condensates.com
It's interesting that phase separation likely plays a role here.
Reviews of physiology, biochemistry and pharmacology
Contributing editor, Condensates.com
This review discusses how the discovery that stress granules form by LLPS has contributed to our current understanding of the role they play in tumorigenesis.