PLoS Pathogens
Most Recent
bioRxiv
Rapid reversible osmoregulation of cytoplasmic biomolecular condensates of human interferon-α-induced antiviral MxA GTPase
Sep
22
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Thursday, September 22, 2022
Nature immunology
IRF3 and IRF7 require SIRT1 for liquid-liquid phase separation and transactivation of INF-I
Jill Bouchard
Editor in Chief, Condensates.com
Here's the Research Briefing associated with the recent Nat Immunol paper about LLPS in innate antiviral immunity.
International journal of molecular sciences
Melatonin: Regulation of Viral Phase Separation and Epitranscriptomics in Post-Acute Sequelae of COVID-19
International journal of biological sciences
Signaling mechanisms of SARS-CoV-2 Nucleocapsid protein in viral infection, cell death and inflammation
Jill Bouchard
Editor in Chief, Condensates.com
This review covers all the ways SARS-CoV-2 uses LLPS to function.
Current protocols
Exploring Manually Curated Annotations of Intrinsically Disordered Proteins with DisProt
Biophysical reviews
A review of the effects of ATP and hydroxychloroquine on the phase separation of the SARS-CoV-2 nucleocapsid protein
Journal of virology
SARS-CoV-2 N Protein Antagonizes Stress Granule Assembly and IFN Production by Interacting with G3BPs to Facilitate Viral Replication
Journal of virology
Role of Stress Granules in Suppressing Viral Replication by the Infectious Bronchitis Virus Endoribonuclease
Frontiers in molecular biosciences
Phase Separation Drives SARS-CoV-2 Replication: A Hypothesis
bioRxiv
Reconstitution of the SARS-CoV-2 ribonucleosome provides insights into genomic RNA packaging and regulation by phosphorylation
Research square
CNBP restricts SARS-CoV2 by regulating IFN and disrupting RNA-protein condensates
Protein & cell
SARS-CoV-2 impairs the disassembly of stress granules and promotes ALS-associated amyloid aggregation
bioRxiv
Contributions of the N-terminal intrinsically disordered region of the SARS-CoV-2 nucleocapsid protein to RNA-induced phase separation
Genome research
Global mapping of RNA homodimers in living cells
bioRxiv
Human coronaviruses disassemble processing bodies
ACS infectious diseases
Intrinsically Disordered Proteins: Perspective on COVID-19 Infection and Drug Discovery
The Journal of biological chemistry
Phase Separation by the SARS-CoV-2 Nucleocapsid Protein: Consensus and Open Questions
Nature chemistry