eLife
Most Recent
Kitchen Table Talk
Must ReadVIDEO: Huaiying Zhang on Liquid-Liquid Phase Separation in Telomere Maintenance of ALT Cancer
bioRxiv
The nanoscale organization of the Wnt signaling integrator Dishevelled in the development-essential vegetal cortex domain of an egg and early embryo
Jill Bouchard
Editor in Chief, Condensates.com
The authors discuss the possibility that these puncta are in fact condensates. I bet we can stay tuned for more experiments on that front.
Genes to cells : devoted to molecular & cellular mechanisms
RNA polymerase II condensate formation and association with Cajal and histone locus bodies in living human cells
Developmental cell
N 6-methyladenosine modification of MALAT1 promotes metastasis via reshaping nuclear speckles
Jill Bouchard
Editor in Chief, Condensates.com
It looks like this lncRNA could be an important scaffold for nuclear speckles. Check out the paper for all the details.
bioRxiv
Phospholipid membrane formation templated by coacervate droplets
bioRxiv
Probe the effect of clustering on EphA2 receptor signaling efficiency by subcellular control of ligand-receptor mobility
Jill Bouchard
Editor in Chief, Condensates.com
This new method gave the authors evidence to support the kinetic proofreading model in condensates.
Cell chemical biology
Reimagining dots and dashes: visualizing structure and function of organelles for high-content imaging analysis
Jill Bouchard
Editor in Chief, Condensates.com
The authors made sure to highlight methods for membraneless organelles too!
bioRxiv
Energetic and structural features of SARS-CoV-2 N-protein co-assemblies with nucleic acids
Nature Biotechnology
Drug startups coalesce around condensates
BioRxiv
RNA polymerase II clusters form in line with liquid phase wetting of chromatin
Analytical chemistry
Dynamic Monitoring of Phase-Separated Biomolecular Condensates by Photoluminescence Lifetime Imaging
Kitchen Table Talk
Must ReadVIDEO: Serena Sanulli on Chromatin and its Phases
Nature
Integrated spatial genomics reveals global architecture of single nuclei
Jill Bouchard
Editor in Chief, Condensates.com
This method could be big for imaging a bunch of nuclear condensates.
ACS Biomaterials Science & Engineering
Single-Cell Quantification of the Transition Temperature of Intracellular Elastin-like Polypeptides
Jill Bouchard
Editor in Chief, Condensates.com
This could be a very useful method for getting #QuantitativeAndRigorousPS data
Nature reviews Molecular cell biology
mRNA translation in stress granules is not uncommon
Jill Bouchard
Editor in Chief, Condensates.com
Here's the preview article for the recent Cell paper about single-molecule imaging of stress granule RNA
Journal of cell science
Polarisome assembly mediates actin remodeling during polarized yeast and fungal growth
Jill Bouchard
Editor in Chief, Condensates.com
And the authors discuss how the phase separation of some IDRs is at the heart of this process.
The journal of physical chemistry B
Controlled Formation of All-Aqueous Janus Droplets by Liquid-Liquid Phase Separation of an Aqueous Three-Phase System
Biomacromolecules
Self-Assembly of Silk-like Protein into Nanoscale Bicontinuous Networks under Phase-Separation Conditions
BioRxiv