BioRxiv
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bioRxiv
ALS-linked mutations impair UBQLN2 stress-induced biomolecular condensate assembly in cells
Cell reports
Phase-Separated Transcriptional Condensates Accelerate Target-Search Process Revealed by Live-Cell Single-Molecule Imaging
Postdoc Positions in Engineering Gas-filled Protein Nanostructures
Rice University | Houston, Texas
ApplyProceedings of the National Academy of Sciences of the United States of America
An intrinsically disordered motif regulates the interaction between the p47 adaptor and the p97 AAA+ ATPase
Jill Bouchard
Editor in Chief, Condensates.com
Here's a thorough biophysical analysis of an IDP involved in membrane remodeling. I bet the methods would also be useful to study condensate-mediated membrane bending.
Molecular reproduction and development
SOX9 is colocalized with paraspeckle protein NONO in cultured murine sertoli cells and features structural characteristics of intrinsically disordered proteins
Jill Bouchard
Editor in Chief, Condensates.com
Here's a nice biophysical analysis of the phase separation of a couple proteins involved in transcription.
Annals of clinical and translational neurology
Localization of CDR2L and CDR2 in paraneoplastic cerebellar degeneration
Jill Bouchard
Editor in Chief, Condensates.com
This article identifies that nuclear speckles may play a key role in this type cancer. I hope it leads to a condensate-based therapeutic!
Nature Cell Biology
Mitochondrial RNA granules are fluid condensates positioned by membrane dynamics
Cell reports
Nuclear Import of the HIV-1 Core Precedes Reverse Transcription and Uncoating
Jill Bouchard
Editor in Chief, Condensates.com
It looks like nuclear speckles play a pretty big role in HIV viral infection.
Molecular & cellular oncology
A single-molecule view of telomerase regulation at telomeres
Jill Bouchard
Editor in Chief, Condensates.com
Here's the author commentary about a recent study about the role of Cajal bodies in telomere regulation.
Postdoc positions at University of California – San Francisco
UCSF | San Francisco, CA
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Leibniz/ FMP | Berlin, Germany
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Radboud University | Nijmegen, Netherlands
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Wednesday, October 7, 2020
Bio-protocol
Spatial Image Correlation Spectroscopy (ICS): A Technique for Average Size Determination of Subcellular Accumulated Structures from Fluorescence Microscopic Images
bioRxiv
The emergence of phase separation as an organizing principle in bacteria
BioRxiv
FUS-dependent liquid-liquid phase separation is an early event in double-strand break repair
Science
Architecture and function of human uromodulin filaments in urinary tract infections
Jill Bouchard
Editor in Chief, Condensates.com
It looks like there's more than just liquid phase in our urine. And these sticky filaments collect bad bacteria and help send them on their way.
bioRxiv
Scaffold-scaffold interactions regulate cell polarity in a bacterium
Jill Bouchard
Editor in Chief, Condensates.com
Cool--The scaffold interactions tune the size and contents of the condensates at the cell poles.
Cell
Genome-Scale Imaging of the 3D Organization and Transcriptional Activity of Chromatin
Jill Bouchard
Editor in Chief, Condensates.com
Here's a bright shiny new imaging technique to help in the quest to study chromosome-containing condensates.