The Journal of biological chemistry
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Viruses
Zinc and Copper Ions Differentially Regulate Prion-Like Phase Separation Dynamics of Pan-Virus Nucleocapsid Biomolecular Condensates
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Nano-Immune-Engineering Approaches to Advance Cancer Immunotherapy: Lessons from Ultra-pH-Sensitive Nanoparticles
Jill Bouchard
Contributing editor, Condensates.com
This review talks about how the field of condensates is intersecting with another hot field: immunotherapy.
eLife
A virus-encoded protein suppresses methylation of the viral genome through its interaction with AGO4 in the Cajal body
Nucleic acids research
Structural analysis of SARS-CoV-2 genome and predictions of the human interactome
Biochemical pharmacology
Pharmacological inhibition of DEAD-Box RNA Helicase 3 attenuates stress granule assembly
Cellular and molecular life sciences : CMLS
IDPology of the living cell: intrinsic disorder in the subcellular compartments of the human cell
PLoS pathogens
Defining the proteolytic landscape during enterovirus infection
Jill Bouchard
Contributing editor, Condensates.com
I wonder how many other condensate proteins get cleaved by this virus? Check out their full catalog to find out more.
Nucleic acids research
Periphilin self-association underpins epigenetic silencing by the HUSH complex
Jill Bouchard
Contributing editor, Condensates.com
All the common features of phase separation (intrinsic disorder, dimerization, and Arg/Tyr low complexity) contribute to fibril and condensate formation here.
mBio
Minimal Elements Required for the Formation of Respiratory Syncytial Virus Cytoplasmic Inclusion Bodies In Vivo and In Vitro
Jill Bouchard
Contributing editor, Condensates.com
Here's a nice article showing RSV inclusion bodies are membraneless organelles formed by LLPS.
Viruses
Functional Characterization of Pepper Vein Banding Virus-Encoded Proteins and Their Interactions: Implications in Potyvirus Infection
Jill Bouchard
Contributing editor, Condensates.com
Here's an interesting review about how a plant virus uses its IDPs for multiple functions... including helping them localize to various membraneless organelles.
Biological reviews of the Cambridge Philosophical Society
Drugs, host proteins and viral proteins: how their promiscuities shape antiviral design
Jill Bouchard
Contributing editor, Condensates.com
Interested in drugging condensates by targeting the IDPs inside? This review should give you a lot of good food for thought.
Chemical communications (Cambridge, England)
Perturbation of liquid droplets of P-granule protein LAF-1 by the antimicrobial peptide LL-III
Cell
Formation of NPR1 Condensates Promotes Cell Survival during the Plant Immune Response
Viruses
Dance with the Devil: Stress Granules and Signaling in Antiviral Responses
Cell
I Will Survive: How NPR1 Condensation Promotes Plant Cell Survival
Jill Bouchard
Contributing editor, Condensates.com
Here’s the Preview article for the Cell paper about the new plant condensates.
Journal of cell science
Mammalian stress granules and P bodies at a glance
Jill Bouchard
Contributing editor, Condensates.com
This review does a nice job of describing the similarities and differences between stress granules and P bodies... obviously one of their commonalities is LLPS ;)
Journal of virology
Respiratory syncytial virus sequesters NF-κB subunit p65 to cytoplasmic inclusion bodies to inhibit innate immune signalling
Jill Bouchard
Contributing editor, Condensates.com
Not all viruses target stress granules: these authors found a virus that uses a different condensate for replication--viral inclusion bodies.