Research Fellow in Protein Chemistry / Biological Mass Spectrometry
University of Leeds | Leeds, United Kingdom
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Journal of virology
Porcine Epidemic Diarrhea Virus Infection Induces Caspase-8 mediated G3BP1 Cleavage and Subverts Stress Granules to Promote Viral Replication
Proceedings of the National Academy of Sciences of the United States of America
Stress granule formation, disassembly, and composition are regulated by alphavirus ADP-ribosylhydrolase activity
Viruses
Reovirus and the Host Integrated Stress Response: On the Frontlines of the Battle to Survive
Jill Bouchard
Contributing editor, Condensates.com
Here's another data point on how viruses use stress granules to evade the immune response.
Feb
04
IDPSeminars: Dorothee Dormann & Sonia Longhi — Feb 4
Thursday, February 4, 2021
PLoS neglected tropical diseases
Relevance of oxidative stress in inhibition of eIF2 alpha phosphorylation and stress granules formation during Usutu virus infection
Jill Bouchard
Contributing editor, Condensates.com
I love seeing all the different ways stress granules are involved in viral infections. Check out our Infectious Disease tag to find others like this.
Molecular biology and evolution
The hunt for ancient prions: Archaeal prion-like domains form amyloid-based epigenetic elements
Jill Bouchard
Contributing editor, Condensates.com
Interesting, I wonder if any of the archaeal prion candidates they found have complex phase diagrams.
Nature communications
The SARS-CoV-2 nucleocapsid phosphoprotein forms mutually exclusive condensates with RNA and the membrane-associated M protein
Viruses
Formation and Function of Liquid-Like Viral Factories in Negative-Sense Single-Stranded RNA Virus Infections
PLoS pathogens
Phase separation and DAXX redistribution contribute to LANA nuclear body and KSHV genome dynamics during latency and reactivation
Biochemical and biophysical research communications
ATP biphasically modulates LLPS of SARS-CoV-2 nucleocapsid protein and specifically binds its RNA-binding domain
The Journal of biological chemistry
Murine GFP-Mx1 forms nuclear condensates and associates with cytoplasmic intermediate filaments: Novel antiviral activity against VSV
bioRxiv
Role of spatial patterning of N-protein interactions in SARS-CoV-2 genome packaging
Jill Bouchard
Contributing editor, Condensates.com
The authors looked into whether the arrangement of LLPS-promoting and solubilizing sequences in the genome lead to single genome packaging. Read on to learn about generalizable principles of virus compaction.
mSphere
Association of Zinc Finger Antiviral Protein Binding to Viral Genomic RNA with Attenuation of Replication of Echovirus 7
Jill Bouchard
Contributing editor, Condensates.com
The authors implicate stress granules and potentially other cellular compartments in mediating antiviral effects.
Microorganisms
Escherichia coli HS and Enterotoxigenic Escherichia coli Hinder Stress Granule Assembly
Jill Bouchard
Contributing editor, Condensates.com
It looks like both good and bad kinds of strains of E. coli have an interesting relationship with stress granules. Check out the details to learn more.
bioRxiv
Rotavirus Replication Factories Are Complex Ribonucleoprotein Condensates
bioRxiv
Poly(ADP-ribose) potentiates ZAP antiviral activity
Jill Bouchard
Contributing editor, Condensates.com
It looks like the ZAP protein has previously been shown to go to stress granules during viral infections and this work suggests it may be triggered by PAR binding.
Cell biology international
Regulation of processing bodies: From viruses to cancer epigenetic machinery
The EMBO journal
Clustering and reverse transcription of HIV-1 genomes in nuclear niches of macrophages
Jill Bouchard
Contributing editor, Condensates.com
It looks like the condensates in infected macrophages get all messed up. Check out this paper to find out more.
PLoS pathogens
The cucumber mosaic virus 1a protein regulates interactions between the 2b protein and ARGONAUTE 1 while maintaining the silencing suppressor activity of the 2b protein
Jill Bouchard
Contributing editor, Condensates.com
This paper is about a cool way a virus involves P-bodies to hide in stealth mode.