eLife

A Gut Bacterial Amyloid Promotes α-Synuclein Aggregation and Motor Impairment in Mice

Jill Bouchard

Contributing editor, Condensates.com

Wow... it's both fascinating and terrifying to think that the bacteria in your gut could cause such long-lasting effects on your brain. It turns out their aggregates are contagious too.

Archives of biochemistry and biophysics

Intrinsically Disordered Protein Domains in Flavivirus Infection

Jill Bouchard

Contributing editor, Condensates.com

Food for thought on why viruses commonly use IDPs in their arsenal, plus some ideas on how we might be able to fight back.

Physical chemistry chemical physics : PCCP

Interfacial Tension and Mechanism of Liquid-Liquid Phase Separation in Aqueous Media

Cell death and differentiation

Spatio-temporal Characterization of the Antiviral Activity of the XRN1-DCP1/2 Aggregation Against Cytoplasmic RNA Viruses to Prevent Cell Death

Jill Bouchard

Contributing editor, Condensates.com

Interesting, it looks like cells have another condensate to take down viral RNA replication, and it could lead to new ideas for antiviral treatments!

Journal of molecular biology

Structural Modeling Using Solution Small-Angle X-ray Scattering (SAXS)

Jill Bouchard

Contributing editor, Condensates.com

For anyone looking to study an IDP or oligomeric protein found in condensates, this review could be informative.

Journal of molecular biology

Structural Basis for Lipid Binding and Function by an Evolutionarily Conserved Protein, Serum Amyloid A

Scientific reports

The Order-Disorder Continuum: Linking Predictions of Protein Structure and Disorder Through Molecular Simulation

International journal of molecular medicine

Effect of eleutheroside B1 on non‑coding RNAs and protein profiles of influenza A virus‑infected A549 cells

Infectious Disease

Journal of virology

The Late Domain of Prototype Foamy Virus Gag Facilitates Autophagic Clearance of Stress Granules by Promoting Amphisome Formation

Infectious Disease

Must Read

FEBS letters

Fuzzy complexes: Specific binding without complete folding

Jill Bouchard

Contributing editor, Condensates.com

This is a nice review detailing our growing understanding of transient interactions... they no doubt also play a large role in condensates.

Must Read

Nature biomedical engineering

A designer molecular chaperone against transmissible spongiform encephalopathy slows disease progression in mice and macaques

Microbial pathogenesis

Nipah shell disorder, modes of infection, and virulence

Infectious Disease

Jill Bouchard

Contributing editor, Condensates.com

An interesting link between protein disorder and a virus's ability to jump hosts. I wonder how this variability also affects the material properties of the virus structure?

Journal of virology

Structure of the 5′ Untranslated Region of Enteroviral Genomic RNA

Infectious Disease

Jill Bouchard

Contributing editor, Condensates.com

It looks like intrinsically disordered RNA is a thing too! IDPs meet IDRRs.

Current opinion in genetics & development

Navigating through the nucleus with a virus

Jill Bouchard

Contributing editor, Condensates.com

This summary of how viruses exploit nuclear architecture could in turn give us insights into how we can exploit them back!

Journal of innate immunity

Innate Immune Evasion by Human Respiratory RNA Viruses

Infectious Disease

Jill Bouchard

Contributing editor, Condensates.com

Every flu season I find myself wondering how they always outsmart us. This review has a nice focus on how they manipulate our stress granules.

Must Read

mBio

Infectious Disease

Infectious Disease

A Gut Bacterial Amyloid Promotes α-Synuclein Aggregation and Motor Impairment in Mice

Jill Bouchard

Intrinsically Disordered Protein Domains in Flavivirus Infection

Jill Bouchard

Interfacial Tension and Mechanism of Liquid-Liquid Phase Separation in Aqueous Media

Spatio-temporal Characterization of the Antiviral Activity of the XRN1-DCP1/2 Aggregation Against Cytoplasmic RNA Viruses to Prevent Cell Death

Jill Bouchard

Structural Modeling Using Solution Small-Angle X-ray Scattering (SAXS)

Jill Bouchard

Structural Basis for Lipid Binding and Function by an Evolutionarily Conserved Protein, Serum Amyloid A

The Order-Disorder Continuum: Linking Predictions of Protein Structure and Disorder Through Molecular Simulation

Effect of eleutheroside B1 on non‑coding RNAs and protein profiles of influenza A virus‑infected A549 cells

The Late Domain of Prototype Foamy Virus Gag Facilitates Autophagic Clearance of Stress Granules by Promoting Amphisome Formation

Fuzzy complexes: Specific binding without complete folding

Jill Bouchard

A designer molecular chaperone against transmissible spongiform encephalopathy slows disease progression in mice and macaques

Nipah shell disorder, modes of infection, and virulence

Jill Bouchard

Structure of the 5′ Untranslated Region of Enteroviral Genomic RNA

Jill Bouchard

Navigating through the nucleus with a virus

Jill Bouchard

Innate Immune Evasion by Human Respiratory RNA Viruses

Jill Bouchard

Phase Transitions Drive the Formation of Vesicular Stomatitis Virus Replication Compartments

Life and Work of Stress Granules and Processing Bodies: New Insights into Their Formation and Function

The Dark Side of Alzheimer’s Disease: Unstructured Biology of Proteins From the Amyloid Cascade Signaling Pathway

RNase L Promotes the Formation of Unique Ribonucleoprotein Granules Distinct From Stress Granules

The Autophagy Protein ATG16L1 Is Required for Sindbis Virus-Induced eIF2α Phosphorylation and Stress Granule Formation

Director of Cardiology (m/f/d)

Post-doc position: Biophysical properties of chromatin

Head of Project and Portfolio Management