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bioRxiv
Sequence determinants of the aggregation of proteins within condensates generated by liquid-liquid phase separation
bioRxiv
ATP biphasically modulates LLPS of TDP-43 PLD by specifically binding arginine residues
The Journal of biological chemistry
Droplet and fibril formation of the functional amyloid Orb2
Briefings in bioinformatics
Proteome-scale analysis of phase-separated proteins in immunofluorescence images
Cell stem cell
Phase separation of OCT4 controls TAD reorganization to promote cell fate transitions
BioRxiv
Sustained Enzymatic Activity and Flow in Crowded Protein Droplets
Scientific reports
Quantitative evaluation of macromolecular crowding environment based on translational and rotational diffusion using polarization dependent fluorescence correlation spectroscopy
Jun
03
SLAS Webinar–Biomolecular Condensates: A Novel Opportunity for Drug Discovery
Thursday, June 3, 2021
ACS chemical neuroscience
C1 Inhibits Liquid-Liquid Phase Separation and Oligomerization of Tau and Protects Neuroblastoma Cells against Toxic Tau Oligomers
Jun
07
Jul
07
VIRTUAL: 35th Anniversary Protein Society Symposium
Wednesday, July 7, 2021
Nature communications
Nucleosome plasticity is a critical element of chromatin liquid-liquid phase separation and multivalent nucleosome interactions
Journal of pharmaceutical sciences
Characterization of opalescence in low volume monoclonal antibody solutions enabled by microscale nephelometry
Jill Bouchard
Managing editor, Condensates.com
I could see these opalescence measurements being pretty valuable for condensate biophysics assays too.
eLife
A subcellular map of the human kinome
Jill Bouchard
Managing editor, Condensates.com
Cool! And these authors found some "kinase condensates" too!
Nucleic acids research
Single-molecule imaging of epigenetic complexes in living cells: insights from studies on Polycomb group proteins
Jill Bouchard
Managing editor, Condensates.com
Spoiler alert, those insights are related to condensates. ;)
bioRxiv
Shape Recovery of Deformed Biomolecular Droplets: Dependence on Condensate Viscoelasticity
Bioinformatics (Oxford, England)
In-silico prediction of in-vitro protein liquid-liquid phase separation experiments outcomes with multi-head neural attention
Scientific reports
PhosIDP: a web tool to visualize the location of phosphorylation sites in disordered regions
Jill Bouchard
Managing editor, Condensates.com
Many researchers are asking how phosphorylation affects condensates. This tool may help you answer them.
The journal of physical chemistry B