Here's the editorial introducing Biochemistry's virtual special issue on Protein Condensates. Make sure to check out all the associated articles with the Biochem special issue tag.

Biomacromolecules

Sequence Context and Complex Hofmeister Salt Interactions Dictate Phase Separation Propensity of Resilin-like Polypeptides

EBioMedicine

Diminished arachidonate 5-lipoxygenase perturbs phase separation and transcriptional response of Runx2 to reverse pathological ventricular remodeling

bioRxiv

Nucleation of Biomolecular Condensates from Finite-Sized Simulations

Small (Weinheim an der Bergstrasse, Germany)

High-Yield Separation of Extracellular Vesicles Using Programmable Zwitterionic Coacervates

International journal of biological macromolecules

Binding of two zinc ions promotes liquid-liquid phase separation of Tau

bioRxiv

Pyrophosphoproteomics: extensive protein pyrophosphorylation revealed in human cell lines

Physical review E

Dynamics of protein condensates in weak-binding regime

Biophysical journal

Aggregation controlled by condensate rheology

bioRxiv

Aliphatic residues contribute significantly to the phase separation of TDP-43 C-terminal domain

Development, growth & differentiation

P-body dynamics revealed by DDX6 protein knockdown via the auxin inducible degron system

Nucleic acids research

rG4detector, a novel RNA G-quadruplex predictor, uncovers their impact on stress granule formation

Array

Must Read

Methods

Mussels Fabricate Porous Glues via Multiphase Liquid-Liquid Phase Separation of Multiprotein Condensates

Rational optimization of a transcription factor activation domain inhibitor

Mapping the Constrained Coding Regions in the human genome to their corresponding proteins

Synthetic protein condensates for cellular and metabolic engineering

SEGCOND predicts putative transcriptional condensate-associated genomic regions by integrating multi-omics data

Regulation of RB1CC1/FIP200 stability and autophagy function by CREBBP-mediated acetylation in an intrinsically disordered region

Programming cell-surface signaling by phase-separation-controlled compartmentalization

Introduction to the Protein Condensates Virtual Special Issue

Jill Bouchard

Sequence Context and Complex Hofmeister Salt Interactions Dictate Phase Separation Propensity of Resilin-like Polypeptides

Diminished arachidonate 5-lipoxygenase perturbs phase separation and transcriptional response of Runx2 to reverse pathological ventricular remodeling

Nucleation of Biomolecular Condensates from Finite-Sized Simulations

High-Yield Separation of Extracellular Vesicles Using Programmable Zwitterionic Coacervates

Binding of two zinc ions promotes liquid-liquid phase separation of Tau

Pyrophosphoproteomics: extensive protein pyrophosphorylation revealed in human cell lines

Dynamics of protein condensates in weak-binding regime

Aggregation controlled by condensate rheology

Aliphatic residues contribute significantly to the phase separation of TDP-43 C-terminal domain

P-body dynamics revealed by DDX6 protein knockdown via the auxin inducible degron system

rG4detector, a novel RNA G-quadruplex predictor, uncovers their impact on stress granule formation

VIDEO: D. Allan Drummond on The Heat Shock Response as a Condensation Response

Senior Manager, Lab Operations and Facilities / Safety Officer (m/f/d)

Head of Translational (Preclinical) Pharmacology – Neurobiology

Head of Translational (Preclinical) Pharmacology – Oncology