Frontiers in Neuroscience

Looking Beyond the Core: The Role of Flanking Regions in the Aggregation of Amyloidogenic Peptides and Proteins

Jill Bouchard

Contributing editor, Condensates.com

Most of the proteins this review covers also undergo LLPS, so the authors discuss the interactions that lead to both solid and liquid phases too.

Frontiers in Molecular Neuroscience

MIRRAGGE – Minimum Information Required for Reproducible AGGregation Experiments

Jill Bouchard

Contributing editor, Condensates.com

This review seeks to provide a roadmap for studying phase separation (mostly for solids and also a little about liquids). It seems to house a wealth of information.

Proceedings of the National Academy of Sciences of the United States of America

Widespread occurrence of the droplet state of proteins in the human proteome

BioRxiv

Choice of fluorophore affects dynamic DNA nanostructures

Jill Bouchard

Contributing editor, Condensates.com

This is a word of caution about using fluorophores to study DNA. The authors showed effects in an aqueous phase separated from actual oil, but I bet similar effects exist in biological condensates.

Journal of chemical theory and computation

Simulation of FUS Protein Condensates with an Adapted Coarse-Grained Model

Must Read

Cell

Single-Molecule Imaging Reveals Translation of mRNAs Localized to Stress Granules

Jill Bouchard

Contributing editor, Condensates.com

Here's a big nail in the coffin for the hypothesis that stress granules are for storage.

Protein science : a publication of the Protein Society

Biomolecular phase separation through the lens of sodium-23 NMR

Must Read

Science (New York, NY)

Protein condensates as aging Maxwell fluids

The journal of physical chemistry B

Molecular Details of Protein Condensates Probed by Microsecond Long Atomistic Simulations

Scientific reports

Dynamics of proteins with different molecular structures under solution condition

Jill Bouchard

Contributing editor, Condensates.com

I wonder if this could become a useful method for looking at proteins in condensates?

Nucleic acids research

PED in 2021: a major update of the protein ensemble database for intrinsically disordered proteins

Jill Bouchard

Contributing editor, Condensates.com

This could be a helpful database to see what certain IDPs might be doing inside condensates.

bioRxiv

Construction of a liquid-liquid phase separation system from the gel-sol transition of elongated protein microgels in a crowding agent

FACULTY POSITION IN MOLECULAR THERAPEUTICS

Fox Chase Cancer Center | Philadelphia, PA, USA

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bioRxiv

The prevalence and distribution in genomes of low-complexity, amyloid-like, reversible, kinked segment (LARKS), a common structural motif in amyloid-like fibrils

GROUP LEADER POSITION IN MOLECULAR LIFE SCIENCES

IMBA - Institute of Molecular Biotechnology | Vienna, Austria

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BioRxiv

Concatemeric Broccoli reduces mRNA stability, aggregates and induces p-body formation

Jill Bouchard

Contributing editor, Condensates.com

You can put aside your love/hate of veggies, these authors were working on finding a way to fluorescently tag RNA but it caused a phase separation response by some unknown mechanism.

Dec

10

Biomolecules

Comparative Assessment of Intrinsic Disorder Predictions with a Focus on Protein and Nucleic Acid-Binding Proteins

Methods

Jill Bouchard

Contributing editor, Condensates.com

If you're on the market for an IDP predictor for your favorite condensate-loving protein, this review should be highly informative.

bioRxiv

Methods

Looking Beyond the Core: The Role of Flanking Regions in the Aggregation of Amyloidogenic Peptides and Proteins

Jill Bouchard

MIRRAGGE – Minimum Information Required for Reproducible AGGregation Experiments

Jill Bouchard

Widespread occurrence of the droplet state of proteins in the human proteome

Choice of fluorophore affects dynamic DNA nanostructures

Jill Bouchard

Simulation of FUS Protein Condensates with an Adapted Coarse-Grained Model

Single-Molecule Imaging Reveals Translation of mRNAs Localized to Stress Granules

Jill Bouchard

Biomolecular phase separation through the lens of sodium-23 NMR

Protein condensates as aging Maxwell fluids

Molecular Details of Protein Condensates Probed by Microsecond Long Atomistic Simulations

Dynamics of proteins with different molecular structures under solution condition

Jill Bouchard

PED in 2021: a major update of the protein ensemble database for intrinsically disordered proteins

Jill Bouchard

Construction of a liquid-liquid phase separation system from the gel-sol transition of elongated protein microgels in a crowding agent

FACULTY POSITION IN MOLECULAR THERAPEUTICS

The prevalence and distribution in genomes of low-complexity, amyloid-like, reversible, kinked segment (LARKS), a common structural motif in amyloid-like fibrils

GROUP LEADER POSITION IN MOLECULAR LIFE SCIENCES

Concatemeric Broccoli reduces mRNA stability, aggregates and induces p-body formation

Jill Bouchard

Emerging Topics in Biomolecular Magnetic Resonance: Mei Hong & Markus Zweckstetter

Identification of the interactomes associated with SCD6 and RBP42 proteins in Leishmania braziliensis

Jill Bouchard

Comparative Assessment of Intrinsic Disorder Predictions with a Focus on Protein and Nucleic Acid-Binding Proteins

Jill Bouchard

Rubisco proton production can drive the elevation of CO2 within condensates and carboxysomes

Biochemist, Postdoc

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