Soft matter
Most Recent
bioRxiv
Transcriptomic and proteomic regulation through abundant, dynamic, and independent arginine methylation by Type I and Type II PRMTs
Jill Bouchard
Editor in Chief, Condensates.com
Here's a new method to look at Arg methylation, and the authors demonstrated an enrichment of it in LLPS.
Proceedings of the National Academy of Sciences of the United States of America
Phase Transition of RNA-protein Complexes Into Ordered Hollow Condensates
Jill Bouchard
Editor in Chief, Condensates.com
So glad to see this work out! We really enjoyed getting a sneak peak at Priya Banerjee's Kitchen Table talk. I hope you'll enjoy the video and paper too!
PhD position – Loquet Lab
European Institute of Chemistry and Biology | Bordeaux, France
ApplyTwo postdoctoral researchers – Lin Huang Lab
Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University | Guangzhou, China
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Single molecule microscopy reveals key physical features of repair foci in living cells
bioRxiv
Nucleocapsid protein of SARS-CoV-2 phase separates into RNA-rich polymerase-containing condensates
Postdoctoral Scholar (Neurodegeneration) – Kraemer Lab
University of Washington | Seattle, WA
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Disordered Proteins Follow Diverse Transition Paths as They Fold and Bind to a Partner
Jill Bouchard
Editor in Chief, Condensates.com
I'd be excited to see if this method can be applied to IDPs inside condensates to understand whats going on in there.
Emerging topics in life sciences
The Multiscale and Multiphase Organization of the Transcriptome
Jill Bouchard
Editor in Chief, Condensates.com
Not every condensate is liquid: This review covers all the different phases used to organize the transcriptome.
Proteins
cnnAlpha: Protein Disordered Regions Prediction by Reduced Amino Acid Alphabets and Convolutional Neural Networks
Jill Bouchard
Editor in Chief, Condensates.com
These authors put machine learning to work for predicting disordered regions. Have you tried it yet? It might turn out to be useful for new proteins found in condensates...
bioRxiv
A predictive coarse-grained model for position-specific effects of post-translational modifications on disordered protein phase separation
The journal of physical chemistry B
A Unified De Novo Approach for Predicting the Structures of Ordered and Disordered Proteins
Science advances
Phase-dependent Redox Insulation in Mussel Adhesion
Jill Bouchard
Editor in Chief, Condensates.com
Cool! Phase separation of mussel foot proteins protects them from oxidation and may be a way of saving up energy!
Postdoc in Protein dynamics & NMR spectroscopy – MULDER lab
Aarhus University | Denmark - The happiest country on earth
ApplyThe Journal of Physical Chemistry Letters
Single-Protein Collapse Determines Phase Equilibria of a Biological Condensate
IDPSeminars: Elizabeth Rhoades & François-Xavier Theillet — July 23
Thursday, July 23, 2020
IDPSeminars: Petur Heidarsson & Jennifer Hurley — August 6
Thursday, August 6, 2020
IDPSeminars: Allan Drummond & Danfeng Cai — August 20
Thursday, August 20, 2020
Frontiers in Physiology
Come Together: Protein Assemblies, Aggregates and the Sarcostat at the Heart of Cardiac Myocyte Homeostasis
Jill Bouchard
Editor in Chief, Condensates.com
This review includes liquid-phase separated bodies in its discussion of aggregates. Check it out to find out why.