Nature communications
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Essays in biochemistry
Functional benefit of structural disorder for the replication of measles, Nipah and Hendra viruses
Life Science Alliance
Regulation of Liprin-α phase separation by CASK is disrupted by a mutation in its CaM kinase domain
Biomacromolecules
Modulating Nanodroplet Formation En Route to Fibrillization of Amyloid Peptides with Designed Flanking Sequences
Nature communications
Protein condensation diseases: therapeutic opportunities
bioRxiv
A multiplex platform to identify mechanisms and modulators of proteotoxicity in neurodegeneration
Angewandte Chemie (International ed in English)
Direct Observation of ‘Elongated’ Conformational States in α-Synuclein upon Liquid-Liquid Phase Separation
Proceedings of the National Academy of Sciences of the United States of America
ALS mutations in the TIA-1 prion-like domain trigger highly condensed pathogenic structures
Nucleic acids research
PhaSepDB in 2022: annotating phase separation-related proteins with droplet states, co-phase separation partners and other experimental information
bioRxiv
Protein structural transitions critically transform the network connectivity and viscoelasticity of RNA-binding protein condensates but RNA can prevent it
bioRxiv
Heterotypic electrostatic interactions control complex phase separation of tau and prion into multiphasic condensates and co-aggregates
bioRxiv
Phosphorylation sites are evolutionary checkpoints against liquid-solid transition in protein condensates
bioRxiv
Direct digital sensing of protein biomarkers in solution
Science translational medicine
Poly(ADP-ribose) promotes toxicity of C9ORF72 arginine-rich dipeptide repeat proteins
Science advances
Uncovering the molecular mechanism for dual effect of ATP on phase separation in FUS solution
bioRxiv
MATR3-antisense LINE1 RNA meshwork scaffolds higher-order chromatin organization
International journal of biological macromolecules
Phase separation of p53 induced by its unstructured basic region and prevented by oncogenic mutations in tetramerization domain
Molecular Cell
Condensed-phase signaling can expand kinase specificity and respond to macromolecular crowding
Biochimica et biophysica acta Molecular cell research
Sequestration of cellular native factors by biomolecular assemblies: Physiological or pathological?
Biology