Essays in biochemistry
Most Recent
Science advances
De novo variants in genes regulating stress granule assembly associate with neurodevelopmental disorders
Nature reviews Drug discovery
Modulating biomolecular condensates: a novel approach to drug discovery
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Interactions of amyloid coaggregates with biomolecules and its relevance to neurodegeneration
Cells
Crosstalk between Biomolecular Condensates and Proteostasis
EBioMedicine
Targeting phosphoglycerate kinase 1 with terazosin improves motor neuron phenotypes in multiple models of amyotrophic lateral sclerosis
Nature communications
Molecular mechanism for the synchronized electrostatic coacervation and co-aggregation of alpha-synuclein and tau
Science advances
Lipid-driven condensation and interfacial ordering of FUS
Frontiers in immunology
Critical Roles of G3BP1 in Red-Spotted Grouper Nervous Necrosis Virus-Induced Stress Granule Formation and Viral Replication in Orange-Spotted Grouper ( Epinephelus coioides)
Sep
21
The Leuven Protein Aggregation Meeting
Wednesday, September 21, 2022 | Leuven, Belgium
Jan
29
Keystone Symposia–Biomolecular Condensates: Emerging Cellular and Biophysical Roles
Sunday, January 29, 2023 | Vancouver, UT, Canada
Array
Must ReadVIDEO: Ankur Jain on Nucleic Acid Phase Separation
ACS chemical neuroscience
Stress Granule Homeostasis, Aberrant Phase Transition, and Amyotrophic Lateral Sclerosis
Nature communications
Single-droplet surface-enhanced Raman scattering decodes the molecular determinants of liquid-liquid phase separation
Science advances
A quantitative biology approach correlates neuronal toxicity with the largest inclusions of TDP-43
Jill Bouchard
Editor in Chief, Condensates.com
This method allowed the authors to "identify and follow, in real time, the contributions of various aspects of TDP-43 localization and aggregation state..." and should be useful for a lot of other disease-related and phase separating proteins.
BMC molecular and cell biology
IDPsBind: a repository of binding sites for intrinsically disordered proteins complexes with known 3D structures
Nature communications
Nanoscale regulation of Ca 2+ dependent phase transitions and real-time dynamics of SAP97/hDLG
International journal of biological sciences
Signaling mechanisms of SARS-CoV-2 Nucleocapsid protein in viral infection, cell death and inflammation
Frontiers in molecular biosciences
Essential Roles and Risks of G-Quadruplex Regulation: Recognition Targets of ALS-Linked TDP-43 and FUS
Antioxidants (Basel, Switzerland)