Must Read

Nature chemistry

The interface of condensates of the hnRNPA1 low-complexity domain promotes formation of amyloid fibrils

Molecular psychiatry

Long non-coding RNA SNHG8 drives stress granule formation in tauopathies

Geriatrics & gerontology international

Stress granule-mediated RNA regulatory mechanism in Alzheimer’s disease

bioRxiv

Intracellular Tau Fragment Droplets Serve as Seeds for Tau Fibrils

ACS chemical neuroscience

Liquid-Liquid Phase Separation (LLPS)-Driven Fibrilization of Amyloid-β Protein

bioRxiv

Rapid optogenetic clustering of a cytoplasmic BcLOV4 variant

bioRxiv : the preprint server for biology

Defining RNA oligonucleotides that reverse deleterious phase transitions of RNA-binding proteins with prion-like domains

Frontiers in molecular neuroscience

Phase separation and pathologic transitions of RNP condensates in neurons: implications for amyotrophic lateral sclerosis, frontotemporal dementia and other neurodegenerative disorders

bioRxiv

ALS-associated FUS mutation reshapes the RNA and protein composition and dynamic of Stress Granules

Neurodegeneration

Nature communications

Cyclic AMP induces reversible EPAC1 condensates that regulate histone transcription

Nature communications

Phase separation of protein mixtures is driven by the interplay of homotypic and heterotypic interactions

Methods in molecular biology (Clifton, NJ)

In Vivo Optogenetic Phase Transition of an Intrinsically Disordered Protein

Proteomics

Proteomics elucidating physiological and pathological functions of TDP-43

Nature communications

Methylene blue accelerates liquid-to-gel transition of tau condensates impacting tau function and pathology

bioRxiv

The ALS/FTD-related C9orf72 hexanucleotide repeat expansion forms RNA condensates through multimolecular G-quadruplexes

Frontiers in bioscience (Landmark edition)

Protein Condensates and Protein Aggregates: In Vitro, in the Cell, and In Silico

Biophysical reviews

(Dys)functional insights into nucleic acids and RNA-binding proteins modulation of the prion protein and α-synuclein phase separation

Communications biology

Atomistic modeling of liquid-liquid phase equilibrium explains dependence of critical temperature on γ-crystallin sequence

BMC genomics

Investigating phase separation properties of chromatin-associated proteins using gradient elution of 1,6-hexanediol

Open research Europe

Neurodegeneration

The interface of condensates of the hnRNPA1 low-complexity domain promotes formation of amyloid fibrils

Long non-coding RNA SNHG8 drives stress granule formation in tauopathies

Stress granule-mediated RNA regulatory mechanism in Alzheimer’s disease

Intracellular Tau Fragment Droplets Serve as Seeds for Tau Fibrils

Liquid-Liquid Phase Separation (LLPS)-Driven Fibrilization of Amyloid-β Protein

Rapid optogenetic clustering of a cytoplasmic BcLOV4 variant

Defining RNA oligonucleotides that reverse deleterious phase transitions of RNA-binding proteins with prion-like domains

Phase separation and pathologic transitions of RNP condensates in neurons: implications for amyotrophic lateral sclerosis, frontotemporal dementia and other neurodegenerative disorders

ALS-associated FUS mutation reshapes the RNA and protein composition and dynamic of Stress Granules

Cyclic AMP induces reversible EPAC1 condensates that regulate histone transcription

Phase separation of protein mixtures is driven by the interplay of homotypic and heterotypic interactions

In Vivo Optogenetic Phase Transition of an Intrinsically Disordered Protein

Proteomics elucidating physiological and pathological functions of TDP-43

Methylene blue accelerates liquid-to-gel transition of tau condensates impacting tau function and pathology

The ALS/FTD-related C9orf72 hexanucleotide repeat expansion forms RNA condensates through multimolecular G-quadruplexes

Protein Condensates and Protein Aggregates: In Vitro, in the Cell, and In Silico

(Dys)functional insights into nucleic acids and RNA-binding proteins modulation of the prion protein and α-synuclein phase separation

Atomistic modeling of liquid-liquid phase equilibrium explains dependence of critical temperature on γ-crystallin sequence

Investigating phase separation properties of chromatin-associated proteins using gradient elution of 1,6-hexanediol

Improved predictions of phase behaviour of intrinsically disordered proteins by tuning the interaction range

Expert in Biomolecular Condensates for The Development of Novel Drugs

Interested in joining Dewpoint Boston?

Interested in joining Dewpoint Dresden?