The Journal of biological chemistry
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Communications biology
A tale of (disordered) tail
Jill Bouchard
Editor in Chief, Condensates.com
Here's the Research Highlight on the recent Nature paper about nucleolar dysfunction in rare genetic diseases.
Communications biology
The association of UBAP2L and G3BP1 mediated by small nucleolar RNA is essential for stress granule formation
Cell reports
YTHDF1 phase separation triggers the fate transition of spermatogonial stem cells by activating the IκB-NF-κB-CCND1 axis
bioRxiv
Benchmarking Molecular Dynamics Force Fields for All-Atom Simulations of Biological Condensates
Frontiers in aging neuroscience
Neuronal biomolecular condensates and their implications in neurodegenerative diseases
bioRxiv
Heterotypic interactions in the dilute phase can drive co-condensation of prion-like low-complexity domains of FET proteins and mammalian SWI/SNF complex
Journal of chemical theory and computation
Optimizing the Martini 3 Force Field Reveals the Effects of the Intricate Balance between Protein-Water Interaction Strength and Salt Concentration on Biomolecular Condensate Formation
International journal of molecular sciences
The Oligomerization Domains of the APC Protein Mediate Liquid-Liquid Phase Separation That Is Phosphorylation Controlled
bioRxiv
Sequence-encoded grammars determine material properties and physical aging of protein condensates
EMBO reports
The fifth element: a novel eIF2α kinase in microglia
Jill Bouchard
Editor in Chief, Condensates.com
Here's the News & Views article introducing the recent article in EMBO Rep demonstrating the role of FAM69C in stress granule assembly.
The Journal of neuroscience : the official journal of the Society for Neuroscience
c-Jun N-terminal Kinase Promotes Stress Granule Assembly and Neurodegeneration in C9orf72-mediated ALS and FTD
Experimental & molecular medicine
Glutathionylation on RNA-binding proteins: a regulator of liquid‒liquid phase separation in the pathogenesis of amyotrophic lateral sclerosis
Nature communications
Amyloid-polysaccharide interfacial coacervates as therapeutic materials
Current opinion in chemical biology
Chemical probes for investigating protein liquid-liquid phase separation and aggregation
Acta neuropathologica
C-terminal frameshift variant of TDP-43 with pronounced aggregation-propensity causes rimmed vacuole myopathy but not ALS/FTD
Science advances
Targeting the NEDP1 enzyme to ameliorate ALS phenotypes through stress granule disassembly
bioRxiv
C9orf72-linked arginine-rich dipeptide repeats aggravate pathological phase separation of G3BP1
Frontiers in molecular biosciences
Reversible protein assemblies in the proteostasis network in health and disease
bioRxiv