Most Recent
Chemistry (Weinheim an der Bergstrasse, Germany)
Contributing editor, Condensates.com
This study applies pressure to a phase-separated neuro-protein interacting with DNA to understand how the DNA is altered long-term.
BioRxiv
Contributing editor, Condensates.com
Interesting... these authors show reversible hydrogels contain amyloid-like fibrils.
Nature Methods
The journal of physical chemistry letters
Radboud University | Nijmegen, Netherlands
ApplyNucleic acids research
Contributing editor, Condensates.com
Do you have a phase-separating protein that looks like it may have an LCD? You can use this online platform to check into it.I’ve saved it in our library of Resources–check it out here: https://condensates.com/resources/platoloco/
Wednesday, May 20, 2020
bioRxiv
Contributing editor, Condensates.com
Isn't it cool that the low complexity domain is required for P-body localization and affects long term memory?!
Trends in biochemical sciences
Contributing editor, Condensates.com
Check this out if you'd like to see how condensates contribute to the formation of fibrillar or crustaceous materials in marine life.
Proceedings of the National Academy of Sciences of the United States of America
Contributing editor, Condensates.com
Here's another study suggesting condensates initiate amyloid formation, except this is in the context of type II diabetes.
Nucleic Acids Research
bioRxiv
Contributing editor, Condensates.com
This work takes a careful look at the roles of specific motifs and residues (mainly poly-Q vs poly-P-II vs VG-repeats) in functional vs pathological amyloids.
iScience
Contributing editor, Condensates.com
Here's an example of the tight regulation of stress granules which keeps neurons working properly.
International journal of molecular sciences
Contributing editor, Condensates.com
Here's an interesting article discussing the relationship between miRNA and the mislocalization of proteins associated with neurodegeneration.
BioRxiv
Molecular brain
Contributing editor, Condensates.com
This work compares how the 'peptide-tails' caused by frameshift disease mutations affect cellular localization.
bioRxiv
Contributing editor, Condensates.com
I find it very interesting that the outer edges of droplets nucleated fibrils.
Biomolecules
Contributing editor, Condensates.com
The advancements made for targeting IDPs will most certainly carry over to condensates.
bioRxiv
Kitchen Table Talk