Most Recent
Stem cells (Dayton, Ohio)
Mesenchymal stromal cells reprogram monocytes and macrophages with processing bodies
Cell biochemistry and function
Novel nucleolar localization of clusterin and its associated functions in human oral cancers: An in vitro and in silico analysis
Jill Bouchard
Editor in Chief, Condensates.com
This paper is about some complex communication between nucleoli and cajal bodies in cancer cells. Check it out to find out more.
Immunity
A Prion-like Domain in Transcription Factor EBF1 Promotes Phase Separation and Enables B Cell Programming of Progenitor Chromatin
Molecular Cell
ALS/FTLD-Linked Mutations in FUS Glycine Residues Cause Accelerated Gelation and Reduced Interactions with Wild-Type FUS
bioRxiv
Mechanistic inferences from analysis of measurements of protein phase transitions in live cells
Nature communications
Small molecules as potent biphasic modulators of protein liquid-liquid phase separation
Science Advances
Small-molecule sequestration of amyloid-β as a drug discovery strategy for Alzheimer’s disease
Spider silk proteins condense into droplets to form silk
Frontiers in plant science
Identification and Characterization of the Heat-Induced Plastidial Stress Granules Reveal New Insight Into Arabidopsis Stress Response
The FEBS Journal
Alternative systems for misfolded protein clearance: life beyond the proteasome
Jill Bouchard
Editor in Chief, Condensates.com
This review discusses the role of phase separation in accumulating misfolded proteins into the various membraneless organelles that are part of a cell's proteostasis network.
Tenure-track Assistant Professor position in Novel Device Technologies Applied to Predictive, Digital, and Personalized Medicine
Boston Univeristy | Boston, MA, USA
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Boston University | Boston, MA, USA
ApplyFrontiers in aging neuroscience
Molecular Chaperones: A Double-Edged Sword in Neurodegenerative Diseases
Jill Bouchard
Editor in Chief, Condensates.com
This review covers the evidence that molecular chaperones are recruited to certain condensates to help preserve the correct material properties for proper function.
Briefings in bioinformatics
MloDisDB: a manually curated database of the relations between membraneless organelles and diseases
Jill Bouchard
Editor in Chief, Condensates.com
Do you want to know what disease(s) your favorite protein or condensate is associated with? You can use this online platform to find out. I’ve saved it in our library of Resources–check it out here: https://condensates.com/resources/mlodisdb/
Frontiers in immunology
Seneca Valley Virus 3C Protease Inhibits Stress Granule Formation by Disrupting eIF4GI-G3BP1 Interaction
Archives of medical research
Role of Chikungunya nsP3 in Regulating G3BP1 Activity, Stress Granule Formation and Drug Efficacy
Jill Bouchard
Editor in Chief, Condensates.com
This article draws some interesting connections between the effects of viruses and cancer on stress granule to figure out how to combat drug resistance in cancer drugs.
BioRxiv
Liquid condensates increase potency of amyloid fibril inhibitors
bioRxiv
Phosphorylation triggers presynaptic phase separation of Liprin-α3 to control active zone structure
The journal of physical chemistry B