BioRxiv
Most Recent
Biochemical Society transactions
Structural insights into glucocorticoid receptor function
Jill Bouchard
Editor in Chief, Condensates.com
This review covers how the IDR of glucocorticoid receptor mediates condensate formation.
Biochemistry
Modularly Built Synthetic Membraneless Organelles Enabling Targeted Protein Sequestration and Release
RNA (New York, NY)
RNA Multimerization as an Organizing Force for Liquid-Liquid Phase Separation
CECAM: From disordered biomolecular complexes to biological coacervates
Tuesday, March 8, 2022 | Zurich, Switzerland
BPS 2022: 66th Annual Biophysical Society Annual Meeting
Saturday, February 19, 2022 | San Francisco, CA, United States
WITHDRAWN: Gordon Research Conference: Protein Folding Dynamics–Folding and Misfolding: Effects of Evolution and Environment (GRC)
Sunday, January 9, 2022 | Oxnard, CA, United States
Nature Chemistry
Catalytic coacervate crucibles
Jill Bouchard
Editor in Chief, Condensates.com
Here's the News & Views article associated with the recent Nat Chem paper about short peptides designed to phase separate and act as microreactors.
WITHDRAWN: Gordon Research Seminar: Protein Folding Dynamics–Folding and Misfolding: Effects of Evolution and Environment (GRS)
Saturday, January 8, 2022 | Oxnard, CA, United States
BioRxiv
MLF2 modulates phase separated nuclear envelope condensates that provoke dual proteotoxicity
RNA
A working model for condensate RNA-binding proteins as matchmakers for protein complex assembly
BioRxiv
The HIV-1 ribonucleoprotein dynamically regulates its condensate behavior and drives acceleration of protease activity through membraneless granular phase separation
The FEBS journal
From structure to molecular condensates: emerging mechanisms for Mediator function
Molecular pharmaceutics
Variable-Temperature NMR Analysis of the Thermodynamics of Polymer Partitioning between Aqueous and Drug-Rich Phases and Its Significance for Amorphous Formulations
Jill Bouchard
Editor in Chief, Condensates.com
Here's a thermodynamic perspective of why some drugs partition into condensates.
eLife
Physical observables to determine the nature of membrane-less cellular sub-compartments
bioRxiv
Implementation of residue-level coarse-grained models in GENESIS for large-scale molecular dynamics simulations
Jill Bouchard
Editor in Chief, Condensates.com
The authors show how their models can be applied to phase-separating IDPs.
Nanoscale
The flexibility-based modulation of DNA nanostar phase separation
RNA biology
Integrated multi-omics reveals common properties underlying stress granule and P-body formation
BioEssays : news and reviews in molecular, cellular and developmental biology
Man does not live by intrinsically unstructured proteins alone: The role of structured regions in aggregation
Jill Bouchard
Editor in Chief, Condensates.com
This review talks about how aggregation plays a role in the formation of reversible granules
Cell