Phase separation — liquid-liquid phase separation, LLPS, or phase transition — is the process by which biomolecular condensates are formed.
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bioRxiv
Contributing editor, Condensates.com
This work takes a careful look at the roles of specific motifs and residues (mainly poly-Q vs poly-P-II vs VG-repeats) in functional vs pathological amyloids.
bioRxiv
Contributing editor, Condensates.com
It's interesting to see how the structures outside and inside condensates matter for function.
bioRxiv
Current opinion in genetics & development
Journal of autoimmunity
Physical review E
Contributing editor, Condensates.com
Do you ever wonder why all the condensates in cells don't fuse into one big one? This review discusses the different physical forces at play.
BioRxiv
bioRxiv
Contributing editor, Condensates.com
I love how phase separation has its hands in membrane curvature.
Nature
bioRxiv
Contributing editor, Condensates.com
I find it very interesting that the outer edges of droplets nucleated fibrils.
Proceedings of the National Academy of Sciences of the United States of America
Biomolecules
Contributing editor, Condensates.com
The advancements made for targeting IDPs will most certainly carry over to condensates.
bioRxiv
Kitchen Table Talk
bioRxiv
Contributing editor, Condensates.com
Meet the newest condensate: L-bodies -- multiphase RNP granules that carry maternal mRNA to oocytes
Nature communications
bioRxiv
Kitchen Table Talk
The journal of physical chemistry B
Contributing editor, Condensates.com
This simulation method might give researchers a nice first approximation for determining phase separation propensity.
Molecular cell
Contributing editor, Condensates.com
Here's a spotlight article on a Nature paper that came out earlier this year connecting phase separation to autophagosome formation.