Interesting-- the redox-related phase separation of a cholesterol transporter may lead to the deposits causing macular degeneration. AND(!) therapeutically restoring function just happens to interfere with condensate formation.

Postepy biochemii

Self-Emergent Protocells Generated in an Aqueous Solution with Binary Macromolecules through Liquid-Liquid Phase Separation

Jill Bouchard

Contributing editor, Condensates.com

Here's some evidence that cells might've just happened spontaneously, thanks to the forces of phase separation.

Physics of Condensates

Blavatnik National Awards for Young Scientists Announce 2020 Laureates

Structural analysis of SARS-CoV-2 genome and predictions of the human interactome

Jill Bouchard

Phase separation drives decision making in cell division

Rohit Pappu on the Molecular Grammar of Biomolecular Condensate Formation and Regulation – Part 1 of 3

Rohit Pappu on the Molecular Grammar of Biomolecular Condensate Formation and Regulation – Part 2 of 3

Rohit Pappu on the Molecular Grammar of Biomolecular Condensate Formation and Regulation – Part 3 of 3

Multiple positions, Castaneda Lab, Syracuse University

Self-assembly of multi-component mitochondrial nucleoids via phase separation

Phase separation as a therapeutic target in tight junction-associated human diseases

Walking Along a Protein Phase Diagram to Determine Coexistence Points by Static Light Scattering

Phase separation of Arabidopsis EMB1579 controls transcription, mRNA splicing, and development

Analysis of Protein Disorder Predictions in the Light of a Protein Structural Alphabet

Jill Bouchard

Christine Mayr on Condensate Networks

Beyond Equilibrium Phase Diagrams: Enzymatic Activity Shakes Up Bacterial Condensates

Jill Bouchard

Biomolecular Condensates in the Nucleus

Jill Bouchard

Apolipoprotein E isoform-specific phase transitions in the retinal pigment epithelium drive disease phenotypes in age-related macular degeneration

Jill Bouchard

[Membraneless organelles and liquid-liquid phase separation – methods for their characterisation]

ATP-Driven Separation of Liquid Phase Condensates in Bacteria

Clusters of bacterial RNA polymerase are biomolecular condensates that assemble through liquid-liquid phase separation

Self-Emergent Protocells Generated in an Aqueous Solution with Binary Macromolecules through Liquid-Liquid Phase Separation

Jill Bouchard

Laboratory Operations Assistant

Acquisition Specialist

Scientist/ Senior Scientist for Cell Applications & Assay Development (m/f/d)