bioRxiv
Most Recent
Protein & cell
CRISPR-assisted transcription activation by phase separation proteins
Nature communications
Alternatively spliced exon regulates context-dependent MEF2D higher-order assembly during myogenesis
medRxiv : the preprint server for health sciences
Long non-coding RNA SNHG8 drives stress granule formation in tauopathies
Frontiers in cell and developmental biology
Dysregulated proteostasis network in neuronal diseases
Nature cancer
Disrupting the phase separation of KAT8-IRF1 diminishes PD-L1 expression and promotes antitumor immunity
Nature communications
Size limits the sensitivity of kinetic schemes
Cell reports
The proteome and transcriptome of stress granules and P bodies during human T lymphocyte activation
Cancer research
Nucleophosmin plays a role in repairing DNA damage and is a target for cancer treatment
Cancer research
LSD1 inhibition disrupts super-enhancer driven oncogenic transcriptional programs in castration-resistant prostate cancer
eLife
Peptides that Mimic RS repeats modulate phase separation of SRSF1, revealing a reliance on combined stacking and electrostatic interactions
BioEssays : news and reviews in molecular, cellular and developmental biology
MED26-containing Mediator may orchestrate multiple transcription processes through organization of nuclear bodies
Proteins
Influence of ALS-linked M337V mutation on the conformational ensembles of TDP-43321-340 peptide monomer and dimer
Journal of fungi (Basel, Switzerland)
Molecular Dissection of Crz1 and Its Dynamic Subcellular Localization in Cryptococcus neoformans
Research square
The cancer testis antigen TDRD1 regulates prostate cancer proliferation by associating with snRNP biogenesis machinery
Viruses
Pro-Viral and Anti-Viral Roles of the RNA-Binding Protein G3BP1
Nucleus (Austin, Tex)
Through the lens of phase separation: intrinsically unstructured protein and chromatin looping
Apr
12
Ben Sabari on Nuclear Organization by Biomolecular Condensates
Wednesday, April 12, 2023
Kitchen Table Talk
Must ReadVIDEO: Dorothee Dormann on Aberrant Phase Transitions of Neurodegeneration-Linked RNA-Binding Proteins: control mechanisms and functional consequences
Proceedings of the National Academy of Sciences