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Cell Proliferation
Super enhancers-Functional cores under the 3D genome
Communications biology
Biomolecular condensates as arbiters of biochemical reactions inside the nucleus
Immunity
It’s a Phase That EBF1 Is Going Through
Jill Bouchard
Contributing editor, Condensates.com
Here's the Preview article for an Immunity paper about a prion-like domain with a pioneering function in transcription.
Cell
RNA-Mediated Feedback Control of Transcriptional Condensates
BioRxiv
Prion-like C-terminal domain of TDP-43 and α-Synuclein interact synergistically to generate neurotoxic hybrid fibrils
Jill Bouchard
Contributing editor, Condensates.com
I find the interplay between TDP-43 and α-Synuclein phase separation very intriguing. How about you?
Frontiers in neurology
Cellular Biology of Tau Diversity and Pathogenic Conformers
Journal of Parkinson's disease
NEAT1 on the Field of Parkinson’s Disease: Offense, Defense, or a Player on the Bench?
Jill Bouchard
Contributing editor, Condensates.com
This review also covers NEAT1's role as a scaffold for paraspeckles.
Current opinion in cell biology
Dealing with DNA lesions: When one cell cycle is not enough
Jill Bouchard
Contributing editor, Condensates.com
This review discusses the role of condensates in DNA damage and repair. Check it out to find out more.
Trends in biochemical sciences
G-Quadruplexes in RNA Biology: Recent Advances and Future Directions
Jill Bouchard
Contributing editor, Condensates.com
This review covers the role of G-quads in phase separation.
Stem Cell Reports
Regulation and Roles of the Nucleolus in Embryonic Stem Cells: From Ribosome Biogenesis to Genome Organization
Jill Bouchard
Contributing editor, Condensates.com
This is a fascinating review about the role of nucleoli in regulating transcription and chromatin structure in stem cells.
BioEssays : news and reviews in molecular, cellular and developmental biology
RNA-protein interactions: Central players in coordination of regulatory networks
Current opinion in genetics & development
Nuclear mechanisms of gene expression control: pre-mRNA splicing as a life or death decision
Jill Bouchard
Contributing editor, Condensates.com
How do nuclear speckles play a role in splicing? Read this to find out.
Developmental cell
Inositol Polyphosphate Multikinase Inhibits Liquid-Liquid Phase Separation of TFEB to Negatively Regulate Autophagy Activity
Emerging Topics in Biomolecular Magnetic Resonance: Mei Hong & Markus Zweckstetter
Thursday, December 10, 2020
Journal of Biochemistry
A dynamic actin-dependent nucleoskeleton and cell identity
The EMBO journal
Clustering and reverse transcription of HIV-1 genomes in nuclear niches of macrophages
Jill Bouchard
Contributing editor, Condensates.com
It looks like the condensates in infected macrophages get all messed up. Check out this paper to find out more.
eLife
Viral-induced alternative splicing of host genes promotes influenza replication
Jill Bouchard
Contributing editor, Condensates.com
It looks like nuclear speckles may be a key location for the splicing agents that help this virus with replication.
International journal of molecular sciences
Liquid-Liquid Phase Separation by Intrinsically Disordered Protein Regions of Viruses: Roles in Viral Life Cycle and Control of Virus-Host Interactions
Nature communications