Epigenetics & chromatin
Most Recent
Biochemical Society transactions
Pluripotency transcription factors at the focus: the phase separation paradigm in stem cells
PLoS genetics
PQN-59 antagonizes microRNA-mediated repression during post-embryonic temporal patterning and modulates translation and stress granule formation in C
Molecular therapy oncolytics
hnRNPK-derived cell-penetratingpeptide inhibits cancer cell survival
BioRxiv
Spatial organization of chromosomes leads to heterogeneous chromatin motion and drives the liquid- or gel-like dynamical behavior of chromatin
Journal of the American Chemical Society
Pressure-Jump Kinetics of Liquid-Liquid Phase Separation: Comparison of Two Different Condensed Phases of the RNA-Binding Protein, Fused in Sarcoma
EMBO reports
Specific RNA interactions promote TDP-43 multivalent phase separation and maintain liquid properties
BMC biology
Formation of nuclear condensates by the Mediator complex subunit Med15 in mammalian cells
Annals of the New York Academy of Sciences
Noncoding RNAs: biology and applications-a Keystone Symposia report
Jill Bouchard
Managing editor, Condensates.com
Check out the latest and greatest condensate biology presented in the Keystone eSymposium "Noncoding RNAs: Biology and Applications" here.
BioRxiv
Host casein kinase 1-mediated phosphorylation modulates phase separation of a rhabdovirus phosphoprotein and virus infection
Kitchen Table Talk
Must ReadVIDEO: Lucia Strader on Condensation to Attenuate Transcriptional Activity in Plants
RNA (New York, NY)
What are the distinguishing features and size requirements of biomolecular condensates and their implications for RNA-containing condensates?
RNA (New York, NY)
RNA in formation and regulation of transcriptional condensates
RNA
Nuage condensates: accelerators or circuit breakers for sRNA silencing pathways?
Nov
18
IDPSeminars: Hagen Hofmann & Josh Riback — November 18
Thursday, November 18, 2021
The Journal of biological chemistry
Proximity-dependent biotinylation detects associations between SARS coronavirus nonstructural protein 1 and stress granule-associated proteins
Jill Bouchard
Managing editor, Condensates.com
It looks like the SARS coronaviruses are similar to many other viruses in that they also hijack condensates. Take a look at this paper to find out the details.
Nucleic acids research
Alternative splicing modulation mediated by G-quadruplex structures in MALAT1 lncRNA
Jill Bouchard
Managing editor, Condensates.com
This paper investigates the structural features of an RNA that scaffolds nuclear speckles.
Cellular & molecular biology letters
The low-complexity domains of the KMT2D protein regulate histone monomethylation transcription to facilitate pancreatic cancer progression
Jill Bouchard
Managing editor, Condensates.com
These authors showed that the LC domains drove the formation of condensates involved in epigenetically stimulating the expression of genes in cancer cells.
Nature structural & molecular biology
Molecular interactions contributing to FUS SYGQ LC-RGG phase separation and co-partitioning with RNA polymerase II heptads
BioRxiv
Sequestration of LINE-1 in novel cytosolic bodies by MOV10 restricts retrotransposition