Video abstract: “A liquid-to-solid phase transition of the ALS protein FUS accelerated by disease mutation”
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Author Anthony Hyman, Simon Alberti, Huyn Kate Lee, Avinash Patel
In this fun video, Tony Hyman, Simon Alberti, Hyun Kate Lee, and Avinash Patel explain their 2015 Cell paper, A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation and the seminal discovery that mutations associated with neurodegeneration cause an aberrant phase transition in FUS biomolecular condensates.