Periphilin self-association underpins epigenetic silencing by the HUSH complex

Authors Daniil M Prigozhin , Christopher H Douse , Laura E Farleigh  , Anna Albecka , Iva A Tchasovnikarova , Richard T Timms , Shun-Ichiro Oda  , Frank Adolf  , Stefan M V Freund , Sarah Maslen , Paul J Lehner , Yorgo Modis  
DetailsDaniil M Prigozhin et al; Nucleic Acids Res; 2020;
DOI10.1093/nar/gkaa785
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Jill Bouchard
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Jill Bouchard
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All the common features of phase separation (intrinsic disorder, dimerization, and Arg/Tyr low complexity) contribute to fibril and condensate formation here.