Science Straight Up: “A heartwarming Tale: How Basic Research into Cell Behavior Spurred an Advance in Transplant Surgery”

Biomolecular condensates impact has expanded its reach into the operating room. Inspired by a recent publication, Lei I, et al, Nat Cardiovascular Res, (2025), Judy Muller and George Lewis at Telluride Science – Science Straight Up, discuss with Dr. Rohit Pappu (Washington University in St. Luis) and Dr. Paul Tang (Mayo Clinic) about the implications of stress-induced condensates in organ transplantation. The conversation underscores the unexpected, life-saving impact of fundamental research on biomolecular condensates, which contributed to advances in organ transplantation, potentially increasing transplant success rates and expanding usable donor hearts. Listen to the podcast here.